Moderate to severe traumatic brain injury frequently results in persistent problems with memory, attention span, mood and more complex brain functioning such as planning and organizing. There are currently no drugs available to reduce the brain damage or the persisting symptoms that result from TBI. The longer term goal of this study is to provide physicians with a safe and effective treatment for TBI.
Eligible patients must be between 16 and 75 years of age admitted to the hospital with moderately severe head injury.
Subjects will be randomly assigned to one of three doses of drug or placebo and will be evaluated for safety and effectiveness. Approximately 260 patients will enroll in the study at multiple locations. More information can be found here.